The more people there are, the more:
- littering
- air pollution (leading to acid rain)
- pavement (less natural infiltration and more surface runoff)
- salt and oil (from roads)
there are. All of those are washed to nearby rivers/streams, forming garbage patches to wherever those waterways lead to.
Toxins and microplastics leak from landfills and infiltrate into waterways, eventually making its way down a human throat, successfully poisoning the human!